[2P] D. Homeostatic and Neuroendocrine Systems

[2P-360] Effects of a Dual Orexin Receptor Blocker Suvorexant on Ventilatory Control

*Isato Fukushi^1,2, Shigefumi Yokota³, Kotaro Takeda^1,4, Jiro Terada⁵, Akira Umeda⁶, Masashi Yoshizawa^1,7, Yosuke Kono^1,7, Yohei Hasebe^1,7, Hiroshi Onimaru⁸, Mieczyslaw Pokorski⁹, Yasumasa Okada¹ (1. Clinical Research Center, Murayama Medical Center, Musashimurayama, Japan, 2. Faculty of Health Sciences, Uekusa Gakuen University, Chiba, Japan, 3. Department of Anatomy and Neuroscience, Shimane University School of Medicine, Izumo, Japan, 4. Faculty of Rehabilitation, School of Healthcare, Fujita Health University, Toyoake, Japan, 5. Department of Pulmonary Medicine, International University of Health and Welfare, School of Medicine, Narita, Japan, 6. Department of General Medicine, School of Medicine, IUHW Shioya Hospital, International University of Health and Welfare, Yaita, Japan, 7. Department of Pediatrics, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan, 8. Department of Physiology, Showa University School of Medicine, Tokyo, Japan, 9. Institute of Health Sciences, University of Opole, Opole, Poland)

Keywords:orexin, suvorexant, hypercapnic ventilatory response, hypoxic ventilatory response