[4O06a1] Autism Spectrum Disorder / Neurodegenerative Disorders

[4O06a1-04] The suppression of autophagic flux from progranulin insufficiency increases aggregate-prone TDP-43 accumulation

*Yoshinori Tanaka¹, Kanami Matsubara¹, Hirotsugu Hino², Yuki Honma¹, Shun-ya Kusumoto¹, Kosuke Takeya¹, Masumi Eto¹ (1. Dept. of Veterinary Medicine, Okayama University of Science, 2. Dept. of Anatomical Scinece, Nihon University School of Medicine)

Keywords:progranulin, TDP-43, autophagy flux, vacuolation