NEURO2022

Presentation information

Symposia

[4S05a] Update of oligonucleotide therapy as a major trend of drug discovery for intractable neurological diseases

Sun. Jul 3, 2022 2:00 PM - 4:00 PM Room 5 (Conference Building B2 (Okinawa Convention Center))

Chair: Takanori Yokota

[4S05a-02] Integrating structure and function to guide development of therapeutic siRNAs for the central nervous system and beyond.

*Chantal Ferguson Ferguson1,2, Julia Alterman1,2, Ken Yamada1,2, Dimas Echeverria1,2, Bruno Godinho1,2,3, Matthew Hassler1,2,3, Neil Aronin1,2,4, Anastasia Khvorova1,2,4 (1. University of Massachusetts Medical School, 2. RNA Therapeutics Institute, 3. Atalanta Therpeutics, 4. Department of Medicine)

Keywords:siRNA, oligonucleotide, chemically modified siRNA, neurodegeneration

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