Yuzo Fujino^1,2, Morio Ueyama^1,3,4, Taro Ishiguro^4,5, Daisaku Ozawa^1,3, Hayato Ito⁶, Asako Murata⁷, Eiichi Tokuda⁸, Yoshiaki Furukawa⁸, Toshiki Mizuno², Hideki Mochizuki⁹, Hidehiro Mizusawa⁵, Keiji Wada⁴, Kinya Ishikawa⁵, Osamu Onodera¹⁰, Kazuhiko Nakatani⁷, Hideki Taguchi⁶, Yoshitaka Nagai^1,3,4,9 (1.Department of Neurology, Kindai University Faculty of Medicine, Japan, 2.Department of Neurology, Kyoto Prefectural University of Medicine, Japan, 3.Department of Neurotherapeutics, Osaka University Graduate School of Medicine, Japan, 4.Department of Degenerative Neurological Diseases, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Japan, 5.Department of Neurology and Neurological Science, Tokyo Medical and Dental University, Japan, 6.School of Life Science and Technology, Tokyo Institute of Technology, Japan, 7.Department of Regulatory Bioorganic Chemistry, The Institute of Scientific and Industrial Research, Osaka University, Japan, 8.Department of Chemistry, Keio University, Japan, 9.Department of Neurology, Osaka University Graduate School of Medicine, Japan, 10.Department of Neurology, Clinical Neuroscience Branch, Brain Research Institute, Niigata University, Japan)

Daiki Takewaki¹, Hiroaki Masuoka², Yuya Kiguchi², Wakiro Sato¹, Wataru Suda², Takashi Yamamura¹ (1.National Center of Neurology and Psychiatry, Department of Immunology, Japan, 2.RIKEN, Laboratory for Microbiome Sciences, Japan)

Masaya Harada^1,2, Katsuhisa Masaki¹, Dai Matsuse¹, Hiroo Yamaguchi^1,3, Yuji Nishimura¹, Ezgi Ozdemir¹, Eizo Tanaka¹, Tatsunori Tanaka⁴, Ryo Yamasaki¹, Hideyuki Takeuchi⁵, Takayuki Taniwaki², Noriko Isobe¹, Jun-ichi Kira^1,6,7 (1.Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Japan, 2.Division of Respirology, Neurology and Rheumatology, Department of Medicine, Kurume University School of Medicine, Japan, 3.School of Physical Therapy, Faculty of Rehabilitation, Reiwa Health Science University, Fukuoka, Japan, 4.Sumitomo Pharma Co., Ltd., Osaka, Japan, 5.School of Medicine Medical Course, Neurology and Stroke Medicine Graduate School of Medicine Degree Program, Yokohama City University, Japan, 6.Translational Neuroscience Center, Graduate School of Medicine, and School of Pharmacy at Fukuoka, International University of Health and Welfare, Japan, 7.Department of Neurology, Brain and Nerve Center, Fukuoka Central Hospital, Japan)

Nobuyuki Eura^1,2, Satoru Noguchi¹, Masashi Ogasawara¹, Aritoshi Iida³, Shinichiro Hayashi¹, Ichizo Nishino¹ (1.Department of Neuromuscular Research, National Center of Neurology and Psychiatry, Japan, 2.Department of Neurology, Nara Medical University, Japan, 3.Medical Genome Center, National Center of Neurology and Psychiatry, Japan)

Sato Yoshidomi¹, Takayuki Fujii¹, Hiroyuki Honda², Kaoru Kashu¹, Yukino Miyachi¹, Hidenori Ogata¹, Ryo Yamasaki¹, Toru Iwaki², Noriko Isobe¹ (1.Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Japan, 2.Department of Neuropathology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Japan)

Kimitoshi Kimura^1,2, Ayshwarya Subramanian^1,2, Zhuoran Yin^1,2, Oleg Butovsky^1,2, Vijay Kuchroo^1,2 (1.Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, USA, 2.Evergrande Center for Immunologic Diseases, Brigham and Women's Hospital and Harvard Medical School, USA)