Tomohiro Imamura^1,2,3, Jun-ichi Kira^1,2,4, Motohiro Yukitake³, Mikio Mitsuishi¹, Guzailiayi Maimaitijiang¹, Xu Zhang¹ (1.Translational Neuroscience Center, Graduate School of Medicine, International University of Health and Welfare, Japan, 2.Department of Pharmaceutical Sciences, School of Pharmacy at Fukuoka, International University of Health and Welfare, Japan, 3.Department of Neurology, Takagi Hospital, International University of Health and Welfare, Japan, 4.Department of Neurology, Brain and Nerve Center, Fukuoka Central Hospital, International University of Health and Welfare, Japan)

Takashi Hosaka^1,2,3, Hiroshi Tsuji¹, Makoto Terada^1,2,3, Yasushi Tomidokoro¹, Akiko Ishii¹, Kiyotaka Nakamagoe¹, Kazuhiro Ishii¹, Akira Tamaoka¹, Shin Kwak⁴ (1.Department of Neurology, Division of Clinical Medicine, Faculty of Medicine, University of Tsukuba, Japan, 2.Ibaraki Western Medical Center, University of Tsukuba Hospital／Jichi Medical University Joint Ibaraki Western Regional Clinical Education Center, Japan, 3.Department of Internal Medicine, Ibaraki Western Medical Center, Japan, 4.Department of Neurology, Tokyo Medical University, Japan)

Soma Furukawa¹, Yuki Fukami¹, Ikuko Yokota², Hisatoshi Hanamatsu³, Jun-ichi Furukawa^2,3, Masaya Hane², Ken Kitajima², Chihiro Sato², Keita Hiraga¹, Satoru Yagi¹, Haruki Koike¹, Masahisa Katsuno¹ (1.Nagoya University Graduate School of Medicine, Department of Neurology, Japan, 2.Institute for Glyco-core Research (iGCORE), Nagoya University, Japan, 3.Department of Orthopaedic Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Japan)

Yoshito Arakaki¹, Shinichi Wada², Sohei Yoshimura¹, Kazunori Toyoda¹, Kazutaka Sonoda³, Michikazu Nakai², Yusuke Sasahara², Masayuki Shiozawa¹, Junpei Koge¹, Akiko Ishigami¹, Kaori Miwa¹, Yoshitaka Iwanaga², Yoshihiro Miyamoto², Kazuo Minematsu⁴, Masatoshi Koga¹ (1.Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, Japan, 2.Department of Medical and Health information Management, National Cerebral and Cardiovascular Center, Japan, 3.Department of Neurology, Saiseikai Fukuoka General Hospital, Japan, 4.Iseikai Corporate Headquarters, Japan)

Takeshi Yoshimoto¹, Ishiyama Hiroyuki¹, Eriko Yamaguchi¹, Yorito Hattori¹, Yasuhisa Akaiwa², Tomoyuki Miyamoto², Michi Kawamoto³, Masahiko Ichijo⁴, Hiroyasu Inoue⁵, Masahiro Oomura⁵, Toshiki Mizuno⁶, Hidekazu Tomimoto⁷, Kazunori Toyoda⁸, Masatoshi Koga⁸, Masafumi Ihara¹ (1.Department of Neurology, National Cerebral and Cardiovascular Center, Japan, 2.Department of Neurology, Dokkyo Medical University Saitama Medical Centre, Japan, 3.Department of Neurology, Kobe City Medical Center General Hospital, Japan, 4.Department of Neurology, Musashino Red Cross Hospital, Japan, 5.Department of Neurology, Nagoya City University Graduate School of Medical Sciences, Japan, 6.Department of Neurology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Japan, 7.Department of Neurology, Graduate School of Medicine, Mie University, Japan, 8.Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, Japan)

Yuki Matsumoto¹, Kimihiko Kaneko¹, Tatsuro Misu¹, Toshiyuki Takahashi², Yoshiki Takai¹, Chihiro Namatame¹, Hiroshi Kuroda^1,3, Kazuo Fujihara⁴, Masashi Aoki¹ (1.Tohoku University Hospital, Department of Neurology, Japan, 2.NHO Yonezawa Hospital, Department of Neurology, Japan, 3.Miyagi Southern Central Hospital, Department of Neurology, Japan, 4.Fukushima Medical University, Department of MS Therapeutics, Japan)