Katsuya Nakamura^1,2, Akiko Sakyu¹, Tsuneaki Yoshinaga², Yoshiki Sekijima² (1.Center for Medical Genetics, Shinshu University Hospital, Japan, 2.Department of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine, Japan)

Keiji Tachikawa, Satomi Mituhashi, Takahiro Shimizu, Takeshi Imai, Yosihisa Yamano (St,marianna univ, Japan)

Riyoko Ko, Takahiro Shimizu, Satomi Mitsuhashi, Kei Kaburagi, Keiji Tachikawa, Yoshihisa Yamano (Division of Neurology, Department of Internal Medicine, St. Marianna University School of Medicine, Japan)

Yosuke Tachibana, Ryusuke Sato, Haruki Makioka, Misuzu Hoshino, Mingshou Jin (Biogen Japan, Japan)

Toru Yamashita, Taijyun Yunoki, Yumi Nakada, Chika Matsuoka, Ryo Sasaki, Ko Tadokoro, Yumiko Nakano, Mami Takemoto, Ryuta Morihara, Hiroyuki Ishiura (Department of Neurology, Okayama University, Japan)