English Poster Session

[Pe-008] English Poster Session 008

Wed. May 31, 2023 5:20 PM - 6:40 PM Poster (幕張メッセ国際展示場 1F 展示ホール7)

Chair:Hideyama Takuto (Tokyo Medical University Hospital, Japan)

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[Pe-008-1] Reduction of GGGGCC repeat RNA by hnRNPA3 suppresses neurodegeneration in C9orf72-ALS/FTD flies

Tomoya Tamiato^1,3, Toshihide Takeuchi^2,3, Morio Ueyama^1,3, Kohji Mori⁴, Manabu Ikeda⁴, Hideki Mochizuki⁵, Yoshitaka Nagai^1,2,3,5 (1.Dept Neurology, Kindai Univ Faculty of Med, Osaka, Japan, 2.Life Science Research Institute, Kindai Univ, Osaka, Japan, 3.Dept Neurotherapeutics, Osaka Univ Grad Sch of Med, Osaka, Japan, 4.Dept Psychiatry, Osaka Univ Grad Sch of Med, Osaka, Japan, 5.Dept Neurology, Osaka Univ Grad Sch of Med, Osaka, Japan)

[Pe-008-2] Simple and efficient scarless genome-editing in patient-derived lymphoblastoid cell lines

Satoshi Yokoi¹, Ryoichi Nakamura², Genki Tohnai², Naoki Atsuta², Yohei Okada³, Gen Sobue⁴, Masahisa Katsuno¹ (1.Department of Neurology, Nagoya University Graduate School of Medicine, Japan, 2.Department of Neurology, Aichi Medical University, Japan, 3.Department of Neural iPSC Research, Institute for Medical Science of Aging, Aichi Medical University, Japan, 4.Aichi Medical University, Japan)

[Pe-008-3] Disease-associated mutations dysregulate phase separation of RBPs in neurodegenerative diseases

Hitoki Nanaura¹, Minako Yamaoka¹, Naohiko Iguchi¹, Takao Kiriyama¹, Eiichiro Mori², Kazuma Sugie¹ (1.Department of Neurology, Nara Medical University, Japan, 2.Department of Future Basic Medicine, Nara Medical University, Japan)

[Pe-008-4] Analysis of TDP-43 pathology for upper motor neurons in ADAR2-conditional knockout mice

Takuto Hideyama, Sayaka Teramoto, Makiko Naito, Jun Yamazaki, Tomoko Saito, Haruhisa Kato, Shin Kwak, Hitoshi Aizawa, Hiroo Terashi (Department of Neurology, Tokyo Medical Hospital, Japan)

[Pe-008-5] A novel reporter, TDP-DiLuc, detects TDP-43 monomerization preceding TDP-43 pathology

Kotaro Oiwa^1,2, Seiji Watanebe², Kazunari Onodera³, Yohei Iguchi¹, Yohei Okada^3,4, Masahisa Katsuno¹, Koji Yamanaka² (1.Department of Neurology, Nagoya University Graduate School of Medicine, Japan, 2.Department of Neuroscience and Pathobiology, Nagoya University Graduate School of Medicine, Nagoya University, Japan, 3.Department of Neural iPSC Research, Institute for Medical Science of Aging, Aichi Medical University, Japan, 4.Department of Neurology, Aichi Medical University School of Medicine, Japan)