Yasumasa Kokubo¹, Ryogen Sasaki², Satoru Morimoto³, Tameko Kihira⁴, Sohei Yoshida⁴ (1.Kii ALS/PDC Research Center, Mie Univ. Graduate School of Regional Innovation Studies, Japan, 2.Dept. of Neurology and Medicine, School of Nursing, Suzuka University of Medical Science, Japan, 3.Dept. of Oncologic Pathology, Mie University, Graduate School of Medicine, Japan, 4.Neurological disease center, Kansai University of Health Sciences, Japan)

Saki Nakashima, Masahiko Tsujita, Jun Tsuruoka, Takeshi Akiba, Hiroaki Koshikawa, Aki Mitsue, Akira Kurita, Kaori Sakuishi (Teikyo University Chiba Medical Center, Department of Neurology, Japan)

Harumi Morioka¹, Takehisa Hirayama¹, Tatsuki Sugisawa², Junpei Nagasawa¹, Masaru Yanagihashi¹, Mari Shibukawa¹, Sayori Hanashiro¹, Junya Ebina¹, Kiyoko Murata¹, Naohiro Washizawa³, Satoru Ebihara⁴, Takashi Nakajima⁵, Yoshitaka Murakami⁶, Osamu Kano¹ (1.Department of Neurology, Toho University Faculty of Medicine, Japan, 2.Department of Rehabilitation, Toho University Faculty of Medicine, Japan, 3.Nutrition Therapy Center, Toho University Faculty of Medicine, Japan, 4.Department of Internal Medicine and Rehabilitation Science, Japan, 5.Departments of Neurology and Rehabilitation Medicine, National Hospital Organization Niigata National Hospital, Japan, 6.Department of Medical Statistics, Toho University Faculty of Medicine, Japan)

Mari Shibukawa¹, Takehisa Hirayama¹, Harumi Morioka¹, Masamichi Hozumi¹, Hiroshi Tsuda¹, Naoki Atsuta², Yuishin Izumi³, Yuki Nakayama⁴, Toshio Shimizu⁵, Haruhisa Inoue⁶, Makoto Urushitani⁷, Koji Yamanaka⁸, Masashi Aoki⁹, Satoru Ebihara¹⁰, Atsushi Takeda¹¹, Osamu Kano¹ (1.Department of Neurology, Toho University Faculty of Medicine, Japan, 2.Department of Neurology, Aichi Medical University School of Medicine, Japan, 3.Department of Neurology, Tokushima University Graduate School of Biomedical Sciences, Japan, 4.Unit for Intractable Disease Nursing Care, Tokyo Metropolitan Institute of Medical Science, Japan, 5.Department of Neurology, Tokyo Metropolitan Neurological Hospital, Japan, 6.Center for iPS Cell Research and Application (CiRA), Kyoto University, Japan, 7.Department of Neurology, Shiga University of Medical Science, Japan, 8.Department of Neuroscience and Pathobiology, Research Institute of Environmental Medicine, Nagoya University, Japan, 9.Department of Neurology, Tohoku University Graduate School of Medicine, Japan, 10.Department of Internal Medicine and Rehabilitation Science, Tohoku University Graduate School of Medicine, Japan, 11.Department of Neurology, National Hospital Organization, Sendai Nishitaga Hospital, Japan)

Chun-zuan Xu^1,2, Su-shan Luo^3,4, Xiao Huan^3,4, Hua-hua Zhong^3,4, Chong-bo Zhao^3,4, Yan Chen^3,4, Zhang-yu Zou^1,2, Sheng Chen^1,2 (1.Department of Neurology, Fujian Medical University Union Hospital, Fuzhou, China, 2.Institute of Clinical Neurology, Fujian Medical University, Fuzhou, China, 3.Department of Neurology, Fudan University Huashan Hospital, Shanghai, China, 4.National Center for Neurological Disorders, Shanghai, China)