[O-46] Oral Session 46

[O-46-3] Development of chemical modifications to overcome neurotoxicity of antisense oligonucleotide

Takayuki Kuroda¹, Kotaro Yoshioka¹, Su Su Lei Mon¹, Toshihiro Sakamoto¹, Maho Katsuyama¹, Kie Yoshida-tanaka¹, Rintaro Iwata-hara¹, Takao Yamaguchi², Tetsuya Nagata¹, Satoshi Obika², Takanori Yokota¹ (1.Department of Neurology and Neurological Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Japan, 2.Bioorganic Chemistry, Graduate School of Pharmaceutical Sciences, Osaka University, Japan)