*Koto Jogasaki^1,2, Yuichi Yamashita¹, Manabu Honda¹ (1. Department of Information Medicine, National Center of Neurology and Psychiatry, Tokyo, Japan, 2. Grad Sch Eng, Tokyo University of Agriculture and Technology, Tokyo, Japan)

*Keiko Iino Ikeda^1,2,3, Hiroshi Onimaru⁴ (1. Dept oral physiol, Sch Dent, Showa Univ, Tokyo, Japan, 2. Innovative Res, Tokyo Inst of Tech, Kanagawa, Japan , 3. Kagawa Nutrition Univ, Tokyo, Japan, 4. Dept physiol, Sch Dent, Showa Univ, Tokyo, Japan)