*Yuki Uchida¹, Shotaro Kamijo², Yuki Samejima^1,3, Masahiro Hosonuma⁴, Hiroshi Onimaru¹, Hikaru Isobe⁴, Motoyasu Honma¹, Yuri Masaoka¹, Masahiko Izumizaki¹ (1. Department of Physiology, Showa University School of Medicine, Tokyo, Japan, 2. Division of Physiology, Toxicology and Therapeutics, Department of Pharmacology, Showa University, Tokyo, Japan, 3. Department of Orthopaedic Surgery, Showa University Fujigaoka Hospital, Yokohama, Japan, 4. Division of Medical Pharmacology, Department of Pharmacology, Showa University School of Medicine, Tokyo, Japan)

*Megumi Uno¹, Junnosuke Nakamura², Huminori Tsuruta³ (1. Coll of Biol Sci, Univ of Tsukuba, Ibaraki, Japan, 2. Doctoral Program in Biol, Univ of Tsukuba, Ibaraki, Japan, 3. Inst of Life and Env Sci, Univ of Tsukuba, Ibaraki, Japan)