*Naoki Mukai¹, Koichi Tanaka², MohammedE Choudhury³, Satoshi Kikuchi¹, Jun Takeba⁴, Norio Sato¹, Junya Tanaka³ (1. Department of Emergency & Critical Care, Grad Sch Med, Ehime Univ, Ehime, Japan, 2. Advanced Emergency and Critical Care Center, Ehime Prefectural Central Hospital, Ehime, Japan, 3. Department of Molecular and Cellular Physiology, Grad Sch Med, Ehime Univ, Ehime, Japan, 4. Department of Emergency & Critical Care, Grad Sch Med, Ehime Univ, Ehime, Japan)