*YouXuan Liu¹, Chia-Hua Lo², Eric Hwang^1,2,3,4 (1. Dept Biol Sci and Technol, Nat'l Yang Ming Chiao Tung Univ, Hsinchu, Taiwan, 2. Inst Mol Med and Bioeng, Nat'l Yang Ming Chiao Tung Univ, Hsinchu, Taiwan, 3. Inst Bioinform and Syst Biol, Nat'l Yang Ming Chiao Tung Univ, Hsinchu, Taiwan, 4. Center for Intell Drug Syst and Smart Bio-devices, Nat'l Yang Ming Chiao Tung Univ, Hsinchu, Taiwan)