*Yuta Sakuragi¹, Xinliang Zhou¹, Chiaki Katagiri¹, Akiyoshi Saito², Hiroshi Nomura³, Masabumi Minami¹ (1. Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan., 2. Laboratory of Pharmacology, Department of Pharmacy, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Japan, 3. Endowed Department of Cognitive Function and Pathology, Institute of Brain Science, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.)