Training School for Next Generation Scientists

[2TS12a] DC, Disease 2

Thu. Jul 25, 2024 4:00 PM - 6:00 PM Room 12 (410)

Senior Discussant: Tadafumi Hashimoto (Department of Degenerative Neurological Diseases, National Center of Neurology and Psychiatry), Chihiro Tohda (Institute of natural Medicine, University of Toyama)
Young Chair: Ayaka Tatsumoto (Doshisha University)

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[2TS12a-01] Identification of candidate key regulators of neural stem cell dynamics and neurogenesis in a transgenic mouse model of Alzheimer’s disease

*Yoshitaka Furuta¹, Jessica Wang¹, Mawada Al Faisal¹, Chia-Hsuan Fu¹, Wangjie Yu¹, Jeannie Chin¹ (1. Dept Neurosci, Baylor College of Medicine, Houston, U.S.A.)

[2TS12a-02] TBK1 activates immunoproteasome via IFNβ and suppresses accumulation of aggregation-prone monomeric TDP-43 and its phosphorylated form

*Shohei Sakai¹, Okiru Komine¹, Seiji Watanabe¹, Kotaro Oiwa^1,2, Koji Yamanaka¹ (1. Dept of Neurosci and Pathobiol, RIEM, Nagoya Univ, Aichi, Japan, 2. Dept of Neurol, Nagoya Univ, Aichi, Japan)

[2TS12a-03] High content screening for modifiers of endogenous wild-type / mutant Tau

*Maika Itsuno¹, Sumihiro Maeda¹, Hideyuki Okano¹ (1. Grad Sch Med, Keio Univ, Tokyo, Japan)

[2TS12a-04] A new transgenic mouse model for functional tracing of circulation via albumin-tagged fluorescent probes

*Xiaowen Wang¹, Marta Vittani¹, Ashley Bomin Lee¹, Yuichi Hiraoka², Ayumu Konno^3,4, Philip Alexander Gade Knak¹, Peter Kusk¹, Masaki Nagao¹, Miho Terunuma⁵, Hirokazu Hirai^3,4, Maiken Nedergaard^1,6, Kohichi Tanaka², Hajime Hirase^1,6 (1. Center for Translational Neuromedicine, University of Copenhagen, Copenhagen, Denmark, 2. Laboratory of Molecular Neuroscience, Medical Research Institute (MRI), Tokyo Medical and Dental University (TMDU), Tokyo, Japan, 3. Department of Neurophysiology and Neural Repair, Gunma University Graduate School of Medicine, Maebashi, Gunma, 371-8511, Japan, 4. Viral Vector Core, Gunma University Initiative for Advanced Research, Maebashi, Gunma, 371-8511, Japan, 5. Division of Oral Biochemistry, Faculty of Dentistry & Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan, 6. Center for Translational Neuromedicine, University of Rochester Medical Center, Rochester, NY, USA)

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