[1P] 68 Neuropsychopharmacology

[1P-311] Ketamine modulates a norepinephrine-astroglial circuit to persistently suppress futility-induced passivity

*Marc Duque Ramirez¹, Alex B Chen², Eric Hsu⁵, Sujatha Narayan², Altyn Rymbek³, Shahinoor Begum⁴, Gesine Saher⁶, Adam E Cohen⁴, David E Olson⁷, Yulong Li⁹, David A Prober³, Dwight E Bergles⁵, Mark C Fishman⁸, Florian Engert¹, Misha B Ahrens² (1. Mol Cell Bio Dept., Harvard Univ, Cambridge, USA, 2. Janelia Research Campus, HHMI, Ashburn, USA, 3. Neuro Dept, Caltech, Pasadena, USA, 4. Chem & Chem Bio, Harvard Univ, Cambridge, USA, 5. Neuro Dept, John Hopkins Univ, Baltimore, USA, 6. Neurogenetics Dept,Max Planck Institute, Göttingen, Germany , 7. Chem Dept, Univ of California Davis, Davis, USA, 8. SCRB Dept, Harvard Univ, Cambridge, USA, 9. PKU-IDG/McGovern Institute for Brain Research, Beijing, China)

Keywords:ketamine, astroglia, norepinephrine, larval zebrafish