[1P] 69 Alzheimer's Disease and Dementia

[1P-317] Overexpression of USP48 Increases the levels of Amyloid Precursor Protein and Amyloid-beta by Inducing Lysosomal Dysfunction through Modulating a TFEB-GSK3beta-dependent pathway

*Yung-Feng Liao¹, Po-Fan Wu¹, Yun-Wen Chen¹ (1. Institute of Cellular and Organismic Biology, Academia Sinica, Taipei, Taiwan)

Keywords:Amyloid precursor protein, Amyloid-beta, Ubiquitin-specific peptidase 48, Alzheimer's disease