[1P] 69 Alzheimer's Disease and Dementia

[1P-319] A Novel Tauopathy Model Mimicking Molecular and Spatial Aspects of Human Tau Pathology

*Rin Yanai¹, Tomoki T Mitani^2,7, Etsuo A Susaki^2,3, Takeharu Minamihisamatsu¹, Masafumi Shimojo¹, Yuri Saito³, Hiroshi Mizuma¹, Nobuhiro Nitta¹, Gen Matsumoto⁴, Kentaro Tanemura⁵, Ming-Rong Zhang¹, Makoto Higuchi¹, Hiroki R Ueda^2,6,7, Naruhiko Sahara¹ (1. National Institutes for Quantum Science and Technology, Chiba, Japan, 2. RIKEN BDR, Suita, Osaka, Japan, 3. Graduate School of Medicine, Juntendo University, Tokyo, Japan, 4. Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, 5. Graduate School of Agricultural Science, Tohoku University, Miyagi, Japan, 6. Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, 7. Graduate School of Medicine, Osaka University, Suita, Osaka, Japan)

Keywords:TAUOPATHY, MODEL MOUSE, TISSUE CLEARING, WHOLE BRAIN