[1P] 69 Alzheimer's Disease and Dementia

[1P-473] Gene expression profiles of orphan G protein-coupled receptors in Alzheimer’s disease model mouse

*Atsushi Shimohata^1,2, Okiru Komine^1,2, Akira Sobue^1,2, Hiroyuki Mizoguchi^3,4, Takashi Saito^1,5, Takaomi C Saido⁶, Naruhiko Sahara⁷, Makoto Higuchi⁷, Koji Yamanaka^1,2 (1. Department of Neuroscience and Pathobiology, Research Institute of Environmental Medicine, Nagoya University, Aichi, Japan., 2. Department of Neuroscience and Pathobiology, Nagoya University Graduate School of Medicine, Japan., 3. Research Center for Next-Generation Drug Development, Research Institute of Environmental Medicine, Nagoya University, Aichi, Japan., 4. Department of Neuropsychopharmacology and Hospital Pharmacy, Nagoya University Graduate School of Medicine, Aichi, Japan., 5. Department of Neurocognitive Science, Institute of Brain Science, Nagoya City University Graduate School of Medical Sciences, Aichi, Japan., 6. Laboratory for Proteolytic Neuroscience, RIKEN Center for Brain Science, Saitama, Japan., 7. Department of Functional Brain Imaging, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.)

Keywords:Alzheimer's disease, Orphan G-protein coupled receptor, Neurodegeneration, Microglia