[1P] 70 Neurodegenerative Disorders

[1P-344] Exploring the molecular mechanisms of cortical synucleinopathies using induced neurons from patient iPSCs

*Hidefumi Suzuki^1,2,3, Naohiro Egawa^1,2,3, Keiko Imamura^2,3,4, Takayuki Kondo^2,3,4, Takako Enami^2,4, Kayoko Tsukita^2,3, Mika Suga^2,3, Yuichiro Yada^2,3, Ran Shibukawa³, Ryosuke Takahashi¹, Haruhisa Inoue^2,3,4 (1. Department of Neurology, Kyoto University Graduate School of Medicine, Kyoto, Japan, 2. Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan, 3. iPSC-based Drug Discovery and Development Team, RIKEN BioResource Research Center, Kyoto, Japan, 4. Medical-risk Avoidance based on iPS Cells Team, RIKEN Center for Advanced Intelligence Project (AIP), Kyoto, Japan)

Keywords:synucleinopathy, cortical neurons, MAPK cascade