[1P] 70 Neurodegenerative Disorders

[1P-352] Neuroprotective Potential of Aminochalcones: Mitigating Neuronal Cell Death through Sirtuin 1 Modulation under Oxidative Stress

*Setthawut Apiraksattayakul¹, Ratchanok Pingaew², Ronnakorn Leechaisit², Veda Prachayasittikul¹, Waralee Ruankham¹, Napat Songtawee¹, Tanawut Tantimongcolwat¹, Somsak Ruchirawat³, Virapong Prachayasittikul¹, Supaluk Prachayasittikul¹, Kamonrat Phopin¹ (1. Med Tech, Mahidol Univ, Nakhon Pathom, Thailand, 2. Fac of Sci, Srinakharinwirot Univ, Bangkok, Thailand, 3. Lab of Med Chem, Chulabhorn Grad Inst, Bangkok, Thailand)

Keywords:Neurodegenerative disease, Oxidative stress, Pharmacokinetic properties, Neuroprotection