[1P] 70 Neurodegenerative Disorders

[1P-478] Mast Cell Degranulation Contributes to Oxaliplatin-Induced Neuropathic Pain Through MRGPRX2/PKCα-dependent TRPV4 Sensitization

*To Jung Tseng^1,2, Ling Hsu¹, Li Hong¹, Chi-Hsien Wu¹, Ying Chen Chi¹, Cheng Tse Wu¹, Yu Chieh Lee¹ (1. Chung Shan Medical University, Taichung, Taiwan, 2. Chung Shan Medical University Hospital, Taichung, Taiwan)

Keywords:Chemotherapy-induced peripheral neuropathy, Neurogenic inflammation, Mast cell degranulation, Neuropathic pain