[1P] 28 Somatosensation

[1P-103] A direct spino-cortical circuit bypassing the thalamus modulates nociception

*Bing Cai^1,2,3, Dan Wu⁴, Hong Xie², Yan Chen^1,2,3, Huadong Wang⁵, Sen Jin⁵, Yuran Song^1,2,3, Anan Li⁶, Shiqi Huang^2,7, Sashuang Wang⁸, Yingjin Lu¹, Lan Bao^1,7,9, Fuqiang Xu⁵, Hui Gong⁶, Changlin Li^1,8, Xu Zhang^1,2,3,7 (1. Guangdong institute of intelligent science and Technology, 2. SIMR Joint Lab of Drug Innovation, Shanghai Advanced Research Institute, Chinese Academy of Sciences (CAS); Xuhui Central Hospital, Shanghai, China, 3. Research Unit of Pain Medicine, Chinese Academy of Medical Sciences, Hengqin, Zhuhai, Guangdong, China., 4. Institute of Neuroscience and State Key Laboratory of Neuroscience, Center for Excellence in Brain Science and Intelligence Technology, CAS, Shanghai, China., 5. Shenzhen Key Laboratory of Viral Vectors for Biomedicine, Brain Cognition and Brain Disease Institute, Shenzhen Institute of Advanced Technology, CAS, Shenzhen, Guangdong, China, 6. HUST-Suzhou Institute for Brainsmatics, JITRI Institute for Brainsmatics, Suzhou, Jiangsu, China., 7. School of Life Science and Technology, ShanghaiTech University, Shanghai, China., 8. Department of Pain Medicine and Shenzhen Municipal Key Laboratory for Pain Medicine, Shenzhen Nanshan People’s Hospital, Shenzhen, Guangdong, China, 9. Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, CAS, Shanghai, China.)

Keywords:Nociception, Ascending pathways, BPN