[2P] 69 Alzheimer's Disease and Dementia

[2P-305] Stimulation of microglial cannabinoid receptor type II improves cognitive decline and neuroinflammation in Alzheimer's disease mice

*Akira Sobue^1,2, Okiru Komine¹, Fumito Endo¹, Yuko Saito³, Shigeo Murayama^3,4, Takashi Saito^1,5, Takaomi Saido⁶, Koji Yamanaka¹ (1. Department of Neuroscience and Pathobiology, Research Institute of Environmental Medicine, Nagoya University, 2. Medical Interactive Research and Academia Industry Collaboration Center, Research Institute of Environmental Medicine, Nagoya University, 3. Brain Bank for Aging Research, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, 4. Brain Bank for Neurodevelopmental, Neurological and Psychiatric Disorders, United Graduate School of Child Development, Osaka University, 5. Department of Neurocognitive Science, Institute of Brain Science, Nagoya City University Graduate School of Medical Sciences, 6. Laboratory for Proteolytic Neuroscience, RIKEN Center for Brain Science)

Keywords:Alzheimer's disease, Microglia, Neuroinflammation