[2P] 70 Neurodegenerative Disorders

[2P-341] Spatial transcriptomics reveals temporal expression changes in the vicinity of α-synuclein that prior to motor dysfunction in a mouse model of multiple system atrophy

*Yoshino Yonezu^1,2, Shogo Tanabe¹, Hidemi Misawa², Rieko Muramatsu¹ (1. Department of Molecular Pharmacology, National Institute of Neuroscience, National Center of Neurology and Psychiatry, 2. Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Keio University)

Keywords:Visium, vascular dysfunction, neuroinflammation, metabolic dysfunction