[2P] 70 Neurodegenerative Disorders

[2P-345] Protein disulfide isomerase promotes liquid-liquid phase separation of TDP-43

*Akira Ishiguro¹, Keiko Nishijima², Yuta Murakami³, Hiroshi kimura³, Shinji Hadano^2,4, Asako Otomo^2,4 (1. Hosei University, 2. Molecular Neuropathobiology Laboratory, Department of Molecular Life Sciences, Tokai University School of Medicine, 3. Graduate School of Engineering, Tokai University, 4. Micro/Nano Technology Center, Tokai University)

Keywords:TDP-43, ALS, LLPS, RNA