[2P] 82 Molecular, Biochemical and Genetic Techniques

[2P-385] A toolkit of highly selective and sensitive genetically encoded neuropeptide sensors

*Huan Wang^1,2, Tongrui Qian^1,2, Yulin Zhao^1,2, Yizhou Zhuo^1,2, Takuya Osakada³, Peng Chen^4,5, Zijun Chen⁶, Huixia Ren⁷, Yuqi Yan^1,2,7, Lan Geng^1,2, Shengwei Fu^1,2,7, Liangyi Chen⁷, Yingjie Zhu⁶, Dayu Lin³, Jiang-Ning Zhou^4,5, Yulong Li^1,2,7,8 (1. Sch Life Sci, Peking Univ, Beijing, China, 2. PKU-IDG/McGovern Institute for Brain Research, Beijing, China, 3. Dept of Psychiatry and Dept of Neuroscience and Physiology, New York Univ Langone Medical Center, New York, NY 10016, USA, 4. Institute of Brain Sci, The First Affiliated Hospital of Anhui Med Univ, Hefei, China., 5. CAS Key Lab of Brain Function and Diseases, Division of Life Sci and Med, Univ of Sci and Tech of China, Hefei, China., 6. BCBDI, Shenzhen Institute of Advanced Technology, CAS, Shenzhen, China, 7. Peking-Tsinghua CLS, Peking Univ, Beijing, China, 8. National Biomedical Imaging Center, Peking University, Beijing, China)

Keywords:Fluorescent sensors, Neuropeptides, G-protein coupled receptors