[2P] 02 Receptors and Transporters

[2P-006] α6GABA_AR-selective positive allosteric modulators as a novel therapy for migraine: A preclinical study in nitroglycerin-induced mouse periorbital allodynia

*Xin Chen Chang¹, Dishary Sharmin³, James Cook³, Lih Chu Chiou^1,2 (1. Graduate Institute of Pharmacology, College of Medicine, National Taiwan University, Taipei, Taiwan, 2. Graduate Institute of Brain and Mind Sciences, College of Medicine, National Taiwan University, Taipei, Taiwan, 3. Department of Chemistry and Biochemistry, University of Wisconsin-Milwaukee, Milwaukee, WI, USA.)

Keywords:Migraine, trigeminal ganglia, GABAA receptor, periorbital allodynia