[2P] 16 Neurogenesis and Gliogenesis

[2P-062] Vitamin C regulates DNA polymerase β-dependent active DNA demethylation and genome stability in cortical development

*Noriyuki Sugo¹, Hiroki Mabuchi¹, Akira Kamiyoshi¹, Mayumi Higuchi¹, Fumihito Miura², Hiromitsu Araki³, Kimi Araki⁴, Takeshi Yagi¹ (1. Grad Sch Frontier Biosciences, Osaka Univ, Osaka, Japan, 2. Kyushu Univ Grad Sch Medical Sciences, Fukuoka, Japan, 3. Kyushu Univ Grad Sch Economics, Fukuoka, Japan, 4. Resource Development and Analysis, Kumamoto Univ, Kumamoto, Japan)

Keywords:active DNA demethylation, DNA double-strand breaks, DNA repair, vitamin C transporter