[2P] 65 Neurodevelopmental disorders including ASD and ADHD

[2P-280] Targeting RNA-splicing to rescue deficits arising from neuropsychiatric-associated heterozygous deletion of neurexin 1

*Hong Lu^1,4, Long Zuo¹, Olivia Lam¹, Sharm Knecht³, Peng Zhang², Rachel Wong³, Ann Marie Craig¹ (1. Dept Psych, Univ of British Columbia, Vancouver, Canada, 2. Dept Neurosci, Case Western Reserve Univ, Cleveland, USA, 3. Dept Biol Struct, Univ of Washington, Seattle, USA, 4. Sch Med, Univ of British Columbia, Vancouver, Canada)

Keywords:alternative splicing, neurexin, neurotransmission, synaptic organizing molecule