[2P] 69 Alzheimer's Disease and Dementia

[2P-314] Activation of GPR34 enhances microglial uptake of amyloid β fibrils

*Sho Takatori¹, Hayato Etani¹, Wenbo Wang¹, Jumpei Omi¹, Aika Akahori¹, Hirotaka Watanabe², Hideyuki Okano², Takashi Saito³, Takaomi C Saido⁴, Toshiyuki Takai⁵, Tomohiko Ohwada¹, Junken Aoki¹, Taisuke Tomita¹ (1. Grad Sch Pharm Sci, Univ Tokyo, Tokyo, Japan, 2. Keio Univ Sch Med, Tokyo, Japan, 3. Grad Sch Med Sci, Nagoya City Univ, Nagoya, Aichi, Japan, 4. RIKEN CBS, Wako, Saitama, Japan, 5. Inst of Dev Aging and Cancer, Tohoku Univ, Sendai, Japan)

Keywords:Alzheimer disease, microglia, amyloid, phagocytosis