[2P] 70 Neurodegenerative Disorders

[2P-330] Monitoring the impact of ALS-associated SQSTM1 mutations on the intracellular dynamics of SQSTM1-bodies using the light-convertible fluorescent protein Dendra2

*Kento Shimakura¹, Chisa Yamaguchi², Haruka Yudahira³, Akira Oka¹, Asako Otomo¹, Shinji Hadano¹ (1. Dept Physiol, Tokai Univ Sch Med, Kanagawa, Japan, 2. Dept Mol Life Sci,Tokai Univ Sch Med, Kanagawa, Japan, 3. Tokyo Met. Neurol. Hosp., Tokyo, Japan)

Keywords:ALS/FTD, SQSTM1, Autophagy, Dendra2