[2P] 70 Neurodegenerative Disorders

[2P-344] Human astrocyte model with mutant D-amino acid oxidase (DAO) using iPSC and CRISPR-Cas9 System

*Hiroya Kobayashi¹, Satoru Morimoto¹, Jumpei Sasabe², Sho Yoshimatu¹, Shiho Nakamura¹, Fumiko Ozawa¹, Emi Qian¹, Selena Setsu⁴, Nicolas Leventoux¹, Shinichi Takahashi^1,3, Hideyuki Okano¹ (1. Department of Physiology, Keio University School of Medicine, 2. Department of Pharmacology, Keio University School of Medicine, 3. Depatment of Neurology and Stroke, Saitama Medical University International Medical Center, Japan, 4. Research Center for Cellular Dynamics, Tokyo University, Japan)

Keywords:AMYOTROPHIC LATERAL SCLEROSIS, GENOME EDITING, iPSC