[2P] 74 Brain and Spinal Cord Injury

[2P-480] Combining a α7 nicotinic acetylcholine receptor allosteric modulator and environmental enrichment improves sustained attention and cholinergic neurotransmission after controlled cortical impact injury in male and female rats

*Eleni Haritomeni Moschonas^1,2,3, Ellen M Annas^1,2, Piper L Rennerfeldt^1,2, Tyler S Ranellone^1,2, Matthew A Bertocchi^1,2, Nicholas S Race^1,2, Jeffrey P Cheng^1,2, Anthony E Kline^1,3,2, Corina O Bondi^1,2,3,4 (1. Physical Medicine and Rehabilitation, University of Pittsburgh, Pittsburgh, PA, 2. Safar Center for Resuscitation Research, Univeristy of Pittsburgh, Pittsburgh, PA, 3. Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA, 4. Neurobiology, University of Pittsburgh, Pittsburgh, PA)

Keywords:Traumatic Brain Injury, Cholinergic neurotransmission, Attention, Enviromental enrichment