NEURO2024

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Training School for Next Generation Scientists

[2TS12m] DC, Disease 1

Thu. Jul 25, 2024 8:45 AM - 10:45 AM Room 12 (410)

Senior Discussant: Koh-ichi Nagata (Department of Molecular Neurobiology, Institute for Developmental Research, Aichi Developmental Disability Center), Yuki Fujita (Graduate School of Medical Research, Shimane University)
Young Chair: Wakana Harigai (Osaka University)

[2TS12m-04] eIF5 stimulates RAN translation from the CUG codon of aberrantly elongated GGGGCC repeat sequence in C9orf72 gene.

*Shiho GOTOH1, Kohji Mori1, Yuzo Fujino 2,3, Yuya Kawabe1, Tomoko Yamashita 1, Tsubasa Omi 1, Kenichi Nagata4, Shinji Tagami1, Yoshitaka Nagai2, Manabu Ikeda1 (1. Psychiatry, Grad Sch Med, Osaka Univ, Suita, Japan , 2. Neurology, Kindai Univ Faculty of Med, Osaka-Sayama, Japan , 3. Neurology, Kyoto Prefectural Univ Med, Kyoto, Japan , 4. Precision Medicine for Dementia, Grad Sch Med, Osaka Univ, Suita, Japan )

Keywords:RAN translation, C9orf72, eIF, FTLD

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