[3P] 63 Depressive and Bipolar disorders

[3P-257] Exploration of disease phenotypes and candidate genes using bipolar disorder family patients derived-iPS neurons.

*Gakuya Takamatsu¹, Yoko Manome⁴, Kaoru Kinjo¹, Kanako Toyama^1,9, Yuko Akamine¹, Kumiko Yanagi⁵, Kae Koganebuchi^3,6, Dimitar Dimitrov⁷, JunSeok Lee¹, Minami Hasegawa⁴, Tomoko Hayakawa^8,1, Tsuyoshi Kondo², Tomoyuki Takahashi⁷, Tadashi Kaname⁵, Hirotaka James Okano⁴, Ryosuke Kimura³, Masayuki Matsushita¹ (1. Department of Molecular & Cellular Physiology, Graduate School of Medicine, University of the Ryukyus, 2. Dept. of Neuropsy., Grad. Sch. of Med., Univ. of the Ryukyus, Okinawa, Japan, 3. Dept. of Hum. Biol. Anat., Grad. Sch. of Med., Univ. of the Ryukyus, Okinawa, Japan, 4. Div. of Regen. Med., Jikei Univ. Sch. of Med., Tokyo, Japan, 5. Dept. of Gen. Med., Natl. Ctr. for Chd. Hlth. Dev., Tokyo, Japan, 6. Dept. of Biol. Sci., Grad. Sch. of Sci., Univ. of Tokyo, Tokyo, Japan, 7. Cel. Mol. Syn. Func. Unit, Okinawa Inst. of Sci. Tech. Grad. Univ., Okinawa, Japan, 8. Dept. of Phamc., Jichi Med. Univ., Tochigi, Japan, 9. Adv.Med. Res. Ctr., Fac. of Med, Univ. of the Ryukyus, Okinawa, Japan)

Keywords:bipolar disorder, iPS cell, differentiation, mitochondria