[3P] 69 Alzheimer's Disease and Dementia

[3P-307] The discrepancy in processing coexisting rival memories in App^NL-G-F knock-in Alzheimer’s disease mouse model

*Mei-Lun Huang¹, Yusuke Suzuki^1,2, Hiroki Sasaguri^3,4, Takaomi Saido³, Itaru Imayoshi^1,2,5 (1. Laboratory of Brain Development and Regeneration, Grad Sch of Biostudies, Kyoto Univ, Kyoto, Japan, 2. Center for Living Systems Information Science (CeLiSIS), Grad Sch of Biostudies, Kyoto Univ, Kyoto, Japan, 3. Laboratory for Proteolytic Neuroscience, RIKEN Center for Brain Science, Saitama, Japan, 4. Dementia Pathophysiology Collaboration Unit, RIKEN Center for Brain Science, Saitama, Japan, 5. Laboratory of Deconstruction of Stem Cells, Institute for Life and Medical Sciences, Kyoto Univ, Kyoto, Japan)

Keywords:Preclinical Alzheimer’s disease , Reinstatement of Associative Fear Memory, Reversal Barnes Maze Spatial Learning