[3P] 11 Gene Regulation

[3P-045] Identification of signaling pathway in BDNF-induced phosphorylation of MRTF pathway and the mutation analyses of putative phosphorylation sites in cortical neurons

*Shigeru Sasaki¹, Shintaro Sakakibara², Daisuke Ihara³, Hiroyuki Sakagami⁴, Hiroaki Sakurai⁵, Akiko Tabuchi³ (1. Lab. Mol. Neurobiol., Grad. Sch. of Med. and Pharm. Sci., Prog. Pharmaceutical Sci., Univ. of Toyama, Toyama, Japan, 2. Lab. Mol. Neurobiol., Grad. Sch. of Med. and Pharm. Sci., Prog. Cognitive and Emotional Neurosci., Univ. of Toyama, Toyama, Japan, 3. Lab. Mol. Neurobiol., Grad. Sch. of Med. and Pharm. Sci., Univ. of Toyama, Toyama, Japan, 4. Dept Anatomy, Kitasato Univ, Sch of Med, Kanagawa, Japan, 5. Lab. Cancer Cell Biol., Grad. Sch. of Med. and Pharm. Sci., Univ. of Toyama, Toyama, Japan)

Keywords:myocardin-related transcription factor, brain-derived neurotrophic factor, phosphorylation, SRF-mediated transcriptional activity