[3P] 82 Molecular, Biochemical and Genetic Techniques

[3P-485] High-efficiency and brain-selective Cre-Lox recombination by AAV-PHP.eB-mediated gene transfer

*Yuuki Kondo^1,2, Yukihiro Ozawa¹, Xinzi Liu^1,2, Miao Pan¹, Yurie Yabuuchi¹, Shin-ichiro Horigane^1,2, Shuhei Ueda^1,2, Ayumu Konno^3,4, Hirokazu Hirai^3,4, Sayaka Takemoto-Kimura^1,2 (1. Department of Neuroscience, Research Institute of Environmental Medicine, Nagoya University, 2. Molecular/Cellular Neuroscience, Nagoya University Graduate School of Medicine, 3. Department of Neurophysiology & Neural Repair, Gunma University Graduate School of Medicine, 4. Viral Vector Core, Gunma University, Initiative for Advanced Research)

Keywords:Cre recombinase, Adeno-associated virus, AAV-PHP.eB, Cre toxicity