[3P] 69 Alzheimer's Disease and Dementia

[3P-300] Intracellular amyloid β protein oligomers disrupt synaptic vesicle recycling through direct interactions with endocytotic machinery.

*Tomoyo Ochiishi¹, Kazuyuki Kiyosue¹, Kazutaka Araki², Kazumi Hirano³, Motomichi Doi³ (1. Biomed Res Inst, Natl Inst of Adv Ind Sci and Technol (AIST), Ibaraki, Japan, 2. Adv Operando-Meas Technol Open Innov Lab, Natl Inst of Adv Ind Sci and Technol (AIST), Chiba, Japan, 3. Cell and Mol Biotech Res Inst, Natl Inst of Adv Ind Sci and Technol (AIST), Ibaraki, Japan)

Keywords:Alzheimer's disease, Aβ oligomer, Endocytosis, Mass spectrometry