Elucidation of the regulatory mechanisms of RAN translation in <em>C9orf72</em>-linked ALS/FTD using <em>Drosophila</em> models

Yuzo Fujino

Presentation information

Symposia

[4S05m] New frontiers of ALS/FTD research by young scientists

Sat. Jul 27, 2024 8:45 AM - 10:45 AM Room 5 (203)

Organizer: Yuka Koike (Department of Molecular Neuroscience, brain Research Institute, Niigata University), Kotaro Oiwa (Department of Neuroscience and Pathobiology, Research Institute of Environmental Medicine, Nagoya University)

[4S05m-01] Elucidation of the regulatory mechanisms of RAN translation in C9orf72-linked ALS/FTD using Drosophila models

*Yuzo Fujino^1,2, Morio Ueyama¹, Daisaku Ozawa¹, Hayato Ito³, Toshiki Mizuno², Osamu Onodera⁴, Hideki Taguchi³, Yoshitaka Nagai^1,5 (1. Department of Neurology, Kindai University Faculty of Medicine, 2. Department of Neurology, Kyoto Prefectural University of Medicine, 3. School of Life Science and Technology, Tokyo Institute of Technology, 4. Department of Neurology, Clinical Neuroscience Branch, Brain Research Institute, Niigata University, 5. Life Science Research Institute, Kindai University)

Keywords:Repeat-associated non-AUG translation, Drosophila, C9orf72-linked ALS/FTD, G-quadruplex structure

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