^○Naoto Watamura¹, Foiani Martha², Duff Karen², Takaomi Saido¹ (1.RIKEN Center for Brain Science, Japan, 2.Dementia Research Institute, University College London, UK)

^○Reona Kobayashi^1,2, Hideyuki Okano^1,2 (1.RIKEN Center for Brain Science, Japan, 2.Department of Physiology, Keio University School of Medicine, Japan)

^○Hiroki Sasaguri^1,2 (1.Laboratory for Proteolytic Neuroscience, RIKEN Center for Brain Science, Japan, 2.Department of Neurology and Neurological Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Japan)

^○Hodaka Yamakado (Department of Neurology Kyoto University Hospital, Japan)

^○Koji Yamanaka (Research Institute of Environmental Medicine, Nagoya University, Japan)