Yo Tsuda¹, Yuta Madokoro¹, Kengo Suzuki¹, Toyohiro Sato¹, Masayuki Mizuno¹, Takashi Saito², Takaomi Saido³, Kosei Ojika¹, Noriyuki Matsukawa¹ (1.Department of Neurology, Nagoya City University, Japan, 2.Department of Neurocognitive science, Nagoya City University, Japan, 3.Laboratory for proteolytic Neuroscience, RIKEN center for Brain science, Japan)

Hidehiro Ishikawa^1,2, Tomonori Hoshino², Gen Hamanaka², Mandeville Emiri², Guo Shuzhen², Shintaro Kimura², Norito Fukuda², Wenlu Li², Akihiro Shindo¹, Sakadzic Sava³, Harrington Mary⁴, Lo Eng², Ken Arai² (1.Department of Neurology, Mie University Graduate School of Medicine, Japan, 2.Neuroprotection Research Laboratories, Departments of Radiology and Neurology, Massachusetts General Hospital and Harvard Medical School, USA, 3.Martinos Center for Biomedical Imaging, USA, 4.Neuroscience Program, Smith College, USA)

Aya Ikeda¹, Manabu Funayama¹, Mari Yoshida², Yuanzhe Li¹, Hiroyo Yoshino¹, Tsuyoshi Inoshita¹, Kahori Shiba³, Hongrui Meng¹, Taku Amo⁴, Ikuko Aiba⁵, Yufuko Saito⁵, Naoki Atsuta⁶, Ryoichi Nakamura⁶, Genki Tohnai⁶, Jun Sone², Yuko Saito⁷, Shigeo Murayama⁷, Yuishin Izumi⁸, Ryuji Kaji⁸, Mitsuya Morita⁹, Asako Tamura¹⁰, Kenya Nishioka¹, Yuzuru Imai¹, Gen Sobue¹¹, Nobutaka Hattori¹ (1.Department of Neurology, Faculty of Medicine, Juntendo University, Japan, 2.Department of Neuropathology, Institute for Medical Science of Aging, Aichi Medical University, Nagakute, Japan, Japan, 3.Department of drug development for Parkinson's disease, Japan, 4.Department of Applied Chemistry, National Defense Academy, Japan, 5.Department of Neurology, NHO Higashinagoya National Hospital, Japan, 6.Department of Neurology, Aichi Medical University, Japan, 7.Department of Neuropathology, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, Japan, 8.Department of Neurology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan, Japan, 9.Division of Neurology, Department of Internal Medicine, Jichi Medical University, Japan, 10.Department of Neurology, Mie University Graduate School of Medicine, Japan, 11.Aichi Medical University, Japan)

Sin Yi Lee¹, Hirotaka Shoji², Aki Shimozawa³, Hirofumi Aoyagi³, Yoshiaki Sato³, Kazuya Tsumagari⁴, Mika Terumitsu³, Junro Kuromitsu³, Jin Nakahara¹, Tsuyoshi Miyakawa², Daisuke Ito⁵ (1.Department of Neurology, Keio University School of Medicine, Japan, 2.Division of Systems Medical Science, Center for Medical Science, Fujita Health University, Japan, 3.Eisai-Keio Innovation Laboratory for Dementia, Human Biology Integration, DHBL, Japan, 4.Proteome Homeostasis Research Unit, RIKEN Center for Integrative Medical Sciences, Japan, 5.Department of Physiology, Keio University School of Medicine, Japan)

Tetsuya Hirato¹, Masanori Sawamura¹, Hideo Tsukada², Tomokazu Nakako³, Tatsuo Nakayama³, Kazuhito Ikeda³, Chen Chih-yang^4,5, Kaoru Isa⁴, Masashi Nakamura⁴, Tadashi Isa⁴, Ryosuke Takahashi¹, Hirotaka Onoe⁶ (1.Department of Neurology, Kyoto University Graduate School of Medicine, Japan, 2.Central Research Laboratory, Hamamatsu Photonics K.K., Japan, 3.Sumitomo Pharma Co., Ltd., Japan, 4.Department of Neuroscience, Kyoto University Graduate School of Medicine, Japan, 5.Kyoto University Institute for the Advanced Study of Human Biology, Japan, 6.Human Brain Research Center, Kyoto University Graduate School of Medicine, Japan)

Tomohisa Yamaguchi¹, Kiyonao Sada³, Nicholas M Kanaan⁴, Shigeo Murayama⁶, Hirohito Sasaki¹, Yen Shu-Hui⁵, Yuki Kitazaki¹, Soichi Enomoto¹, Norimichi Shirafuji¹, Masamichi Ikawa¹, Osamu Yamamura¹, Tadanori Hamano^1,2,4 (1.Department of Neurology, University of Fukui Hospital, Japan, 2.Department of Aging and Dementia (DAD), Faculty of Medical Sciences, University of Fukui Hospital, Japan, 3.Department of Genome Science and Microbiology, Faculty of Medical Sciences, University of Fukui Hospital, Japan, 4.Michigan State University, College of Human Medicine, USA, 5.Mayo Clinic Jacksonville, USA, 6.Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, Japan)

Ryo Iwase, Taro Ishiguro, Tetsuya Nagata, Rintaro Iwata-Hara, Takanori Yokota (Department of Neurology and Neurological Science, Tokyo Medical and Dental University, Japan)