Shusuke Koto, Norio Chihara, Kyoka Shiroma, Asato Tsuji, Kimitaka Katanazaka, Shota Nishii, Kento Matoba, Ritsu Akatani, Masaya Togo, Kenji Sekiguchi, Riki Matsumoto (Division of Neurology, Kobe University Graduate School of Medicine, Japan)

Masaaki Niino¹, Shoko Fukumoto², Yusei Miyazaki¹, Nobuo Sanjo³, Takashi Ohashi^4,5, Hideyuki Takeuchi^6,7, Juichi Fujimori⁸, Tatsusada Okuno⁹, Hikoaki Fukaura¹⁰, Yuko Shimizu¹¹, Eri Takahashi¹, Nobuhiro Mifune¹² (1.Department of Clinical Research, National Hospital Organization Hokkaido Medical Center, Japan, 2.Department of Neurology, Kyushu University, Japan, 3.Department of Neurology and Neurological Science, Tokyo Medical and Dental University, Japan, 4.Department of Neurology, Kamagaya General Hospital, Japan, 5.Department of Neurology, Tokyo Women's Medical University Yachiyo Medical Center, Japan, 6.Department of Neurology, Graduate School of Medicine, International University of Health and Welfare, Japan, 7.Department of Neurology and Stroke Medicine, Yokohama City University Graduate School of Medicine, Japan, 8.Division of Neurology, Tohoku Medical and Pharmaceutical University, Japan, 9.Department of Neurology, Osaka University Graduate School of Medicine, Japan, 10.Department of Neurology, Saitama Medical Center, Saitama Medical University, Japan, 11.Department of Medical Safety and Department of Neurology, Tokyo Women's Medical University School of Medicine, Japan, 12.School of Economics and Management, Kochi University of Technology, Japan)

Katsuichi Miyamoto¹, Norimitsu Inoue², Hidefumi Ito¹ (1.Department of Neurology, Wakayama Medical University, Japan, 2.Department of Molecular Genetics, Wakayama Medical University, Japan)

Chihiro Fujii^1,2, Yuta Kojima², Shinji Ashida², Kumi Ishii¹, Yuya Shinoto¹, Kenji Yoshinaga¹, Rie Tohge¹, Masaki Takata¹, Ryusei Nishigori¹, Mio Hamatani¹, Yusuke Yakushiji³, Takayuki Kondo¹ (1.Department of Neurology, Kansai Medical University Medical Center, Japan, 2.Department of Neurology, Kyoto Prefectural University of Medicine, Japan, 3.Department of Neurology, Kansai Medical University, Japan)

Ritsu Akatani, Norio Chihara, Atsushi Hara, Asato Tsuji, Shusuke Koto, Riki Matsumoto (Division of Neurology, Kobe University Graduate School of Medicine, Japan)

Naoya Yamazaki¹, Tatsuro Misu¹, Naoki Yamamoto¹, Shu Umezawa¹, Naohiro Sakamoto¹, Chihiro Namatame¹, Yuki Matsumoto¹, Hirohiko Ono¹, Kimihiko Kaneko¹, Yoshiki Takai¹, Hiroshi Kuroda^1,2,3, Kazuo Fujihara^1,2,3, Masashi Aoki¹ (1.Department of Neurology, Tohoku University Graduate School of Medicine, Japan, 2.Multiple Sclerosis &Neuromyelitis Optica Center, Southern TOHOKU Research Institute for Neuroscience, Japan, 3.Department of Multiple Sclerosis Therapeutics, Fukushima Medical University, Japan)