Fumihiro Yanagimura^1,5, Akihiro Nakajima¹, Etsuji Saji¹, Takashi Nakajima⁵, Hiroshi Shimizu², Yasuko Toyoshima^2,8, Akiyoshi Kakita², Hitoshi Takahashi^6,7, Masatoyo Nishizawa^4,7, Osamu Onodera¹, Izumi Kawachi^1,3 (1.Department of Neurology, Brain Research Institute, Niigata University, Japan, 2.Department of Pathology, Brain Research Institute, Niigata University, Japan, 3.Comprehensive Medical Education Center, Niigata University School of Medicine, Japan, 4.Niigata University of Health and Welfare, Japan, 5.Department of Neurology, NHO Niigata National Hospital, Japan, 6.Niigata Neurosurgical Hospital, Japan, 7.Brain Research Institute, Niigata University, Japan, 8.Agano Hospital, Japan)

Takayuki Fujii, Yuka Inoue, Mitsuru Watanabe, Katsuhisa Masaki, Noriko Isobe (Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Japan)

Kimihiko Kaneko¹, Hiroshi Kuroda^1,2,3, Yuki Matsumoto^1,2,4, Naohiro Sakamoto¹, Shu Umezawa¹, Naoki Yamamoto¹, Naoya Yamazaki¹, Chihiro Namatame¹, Hirohiko Ono¹, Yoshiki Takai¹, Toshiyuki Takahashi^1,5, Juichi Fujimori⁶, Ichiro Nakashima⁶, Yasuo Harigaya⁷, Kazuo Fujihara^1,2,3, Tatsuro Misu¹, Masashi Aoki¹ (1.Department of Neurology, Tohoku University Graduate School of Medicine, Japan, 2.Southern TOHOKU Research Institute for Neuroscience Southern TOHOKU General Hospital, Japan, 3.Department of Multiple Sclerosis Therapeutics, Fukushima Medical University, Japan, 4.Department of Neurology, NHO Miyagi National Hospital, Japan, 5.Department of Neurology, NHO Yonezawa National Hospital, Japan, 6.Department of Neurology, Tohoku Medical and Pharmaceutical University, Japan, 7.Department of Neurology, Japanese Redcross Maebashi Hospital, Japan)

Jun-ichi Kira^1,2,3, Maimaitijiang Guzailiayi², Ayako Sakoda^1,2, Mitsuru Watanabe⁴, Satoshi Nagata⁴, Ozdemir Ezgi⁴, Katsuhisa Masaki⁴, Ryo Yamasaki⁴, Noriko Isobe⁴, Xu Zhang², Tomohiro Imamura^2,3, Yuri Nakamura^1,2,3 (1.Department of Neurology, Brain and Nerve Center, Fukuoka Central Hospital, International University of Health and Welfare, Japan, 2.Translational Neuroscience Research Center, Graduate School of Medicine, International University of Health and Welfare, Japan, 3.School of Pharmacy at Fukuoka, International University of Health and Welfare, Japan, 4.Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Japan)

Cossu Davide^1,2, Yuji Tomizawa¹, Sechi Leonardo A.², Nobutaka Hattori¹ (1.Juntendo University, Japan, 2.Sassari University, Italy)

Siwakorn Chaiyanarm¹, Piraya Satiraphan¹, Natnasak Apiraksattayakul², Jiraporn Jitprapaikulsan^2,3, Weerapat Owattanapanich⁴, Tarinee Rungjirajittranon⁴, Witsarut Nanthasi³ (1.Faculty of Medicine Siriraj Hospital, Mahidol University, Thailand, 2.Siriraj Neuroimmunology Center, Division of Neurology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Thailand, 3.Division of Neurology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Thailand, 4.Division of Hematology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Thailand)