[O-43] Oral Session 43 ［English］「Motor neuron disease 2」

Sat. Jun 1, 2024 8:00 AM - 9:30 AM Room6 (Hall D7, D Block, 7F, TIF)

Chair(s): Makito Hirano (Kindai University Faculty of Medicine, Department of Neurology, Japan), Akihiro Hashiguchi (Kagoshima University Hospital, Neurological Disease Center, Neurology, Japan)

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[O-43-1] Safety and Clinical Effects of Muse Cells in Patients with Amyotrophic Lateral Sclerosis

Toru Yamashita¹, Yumiko Nakano¹, Ryo Sasaki¹, Koh Tadokoro¹, Yoshio Omote¹, Taijun Yunoki¹, Yuko Kawahara¹, Namiko Matsumoto¹, Yuki Taira¹, Chika Matsuoka¹, Ryuta Morihara¹, Koji Abe² (1.Department of Neurology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Japan, 2.Department of Neurology, National Center of Neurology and Psychiatry, Japan)

[O-43-2] Role of regulatory T cells in the pathogenesis of amyotrophic lateral sclerosis (ALS)

Seiichi Nagano^1,2, Yoshiaki Yasumizu³, Reo Morimoto³, Mika Nakayama^1,3, Takuya Sumida³, Norihisa Mikami³, Shimon Sakaguchi³, Hideki Mochizuki² (1.Department of Neurotherapeutics, Osaka University Graduate School of Medicine, Japan, 2.Department of Neurology, Osaka University Graduate School of Medicine, Japan, 3.Experimental Immunology, Immunology Frontier Research Center, Osaka University, Japan)

[O-43-3] Low parvalbumin in CSF is the first promising histopathology-related biomarker for sporadic ALS

Shintaro Hayashi^1,2, Ryo Yamasaki¹, Yuko Kobayakawa¹, Jun-ichi Kira^3,4, Noriko Isobe¹ (1.Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Japan, 2.Department of Neurology, Gunma Rehabilitation Hospital, Japan, 3.Translational Neuroscience Research Center, Graduate School of Medicine, and School of Pharmacy at Fukuoka, International University of Health and Welfare, Japan, 4.Department of Neurology, Brain and Nerve Center, Fukuoka Central Hospital, Japan)

[O-43-4] Increased synaptic gene expression in oligodendrocytes in spinal and bulbar muscular atrophy

Madoka Iida¹, Kentaro Sahashi¹, Tomoki Hirunagi¹, Kenji Sakakibara¹, Kentaro Maeda¹, Tomohiro Akashi², Kunihiko Hinohara^2,3,4, Masahisa Katsuno^1,5 (1.Department of Neurology, Nagoya University Graduate School of Medicine, Japan, 2.Center for 5D Cell Dynamics, Nagoya University Graduate School of Medicine, Japan, 3.Department of Immunology, Nagoya University Graduate School of Medicine, Japan, 4.Institute for Advanced Research, Nagoya University, Japan, 5.Department of Clinical Research Education, Nagoya University Graduate School of Medicine, Japan)

[O-43-5] Development of a novel, rapid and easy-to-use SMA screening kit

Masaki Hirano^1,2, Kentaro Sahashi³, Yuki Ichikawa², Atsushi Natsume⁴, Masahisa Katsuno³ (1.Tokai Central Hospital, Japan, 2.Craif Inc., Japan, 3.Department of Neurology, Nagoya University Graduate School of Medicine, Japan, 4.Institute of Innovation for Future Society of Nagoya University, Japan)

[O-43-6] Treatment of neonatal synaptic abnormalities rescues polyQ-mediated neuronal pathology in SBMA mice

Tomoki Hirunagi¹, Kentaro Sahashi¹, Madoka Iida¹, Kenji Sakakibara¹, Kentaro Maeda¹, Masahisa Katsuno^1,2 (1.Department of Neurology, Nagoya University Graduate School of Medicine, Japan, 2.Department of Clinical Research Education, Nagoya University Graduate School of Medicine, Japan)