Monami Osawa¹, Yuanzhe Li¹, Hiroyo Yoshino², Yuka Suganuma¹, Manabu Funayama^1,2, Nobutaka Hattori^1,2,3 (1.Department of Neurology, Faculty of Medicine, Juntendo University, Japan, 2.Research Institute for Diseases of Old Age, Graduate School of Medicine, Juntendo University, Japan, Japan, 3.Neurodegenerative Disorders Collaborative Laboratory, RIKEN Center for Brain Science, Japan)

Manabu Funayama^1,2,9, Kensuke Daida^2,3,4, Billingsley Kimberley³, Malik Laksh⁴, Miano-burkhardt Abigail³, Leonard Hampton^3,4,5,6, Makarious Mary^3,7,8, Hirotaka Iwaki^4,5, Ding Jinhui³, Gibbs Raphael³, Mayu Ishiguro², Hiroyo Yoshino¹, Kotaro Ogaki², Genko Oyama², Kenya Nishioka², Risa Nonaka^2,9, Wado Akamatsu⁹, Blauwendraat Cornelis^3,4, Nobutaka Hattori^1,2,9,10 (1.Research Institute for Diseases of Old Age, Graduate School of Medicine, Juntendo University, Japan, 2.Department of Neurology, Faculty of Medicine, Juntendo University, Japan, 3.Laboratory of Neurogenetics, NIA, NIH, USA, 4.Center for Alzheimer's and Related Dementias (CARD), NIA, NINDS, NIH, USA, 5.Data Tecnica International LLC, USA, 6.German Center for Neurodegenerative Diseases (DZNE), Germany, 7.Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, UK, 8.UCL Movement Disorders Centre, University College London, UK, 9.Center for Genomic and Regenerative Medicine, Graduate School of Medicine, Juntendo University, Japan, 10.Neurodegenerative Disorders Collaborative Laboratory, RIKEN Center for Brain Science, Japan, Japan)

Mayu Ishiguro¹, Manabu Funayama^1,2,3, Taku Hatano¹, Hiroshi Nishida⁴, Yuko Wada⁵, Kazuyuki Noda⁶, Masahiko Tomiyama⁷, Hiroyo Yoshino², Yuanzhe Li^1,8, Ong Stephanie^1,3, Cioffi Ettore¹, Kenya Nishioka⁹, Nobutaka Hattori^1,2,3,8,10 (1.Department of Neurology, Faculty of Medicine, Juntendo University, Japan, 2.Research Institute for Diseases of Old Age, Graduate School of Medicine, Juntendo University, Japan, 3.International Collaborative Research Administration, Juntendo University, Japan, 4.Department of Neurology, Gifu Prefectural General Medical Center, Japan, 5.Department of Neurology, Rakuwa-kai Otowa hospital, Japan, 6.Department of Neurology, Juntendo University Shizuoka Hospital, Japan, 7.Department of Neurology, Institute of Brain Science, Hirosaki University Graduate School of Medicine, Japan, 8.Department of Diagnosis, Prevention and Treatment of Dementia, Graduate School of Medicine, Juntendo University, Japan, 9.Department of Neurology, Juntendo Tokyo Koto Geriatric Medical Center, Japan, 10.Neurodegenerative Disorders Collaborative Laboratory, RIKEN Center for Brain Science, Japan)

Hidefumi Suzuki^1,2,3, Naohiro Egawa^1,2,3, Keiko Imamura^2,3,4, Takayuki Kondo^2,3,4, Kayoko Tsukita^2,3, Ayako Nagahashi^2,4, Takako Enami^2,4, Kazuko Hasegawa⁵, Hirofumi Maruyama⁶, Hideyuki Sawada⁷, Tomoko Oeda⁷, Mitsuo Kodama⁸, Tsuyoshi Uchiyama⁹, Ryosuke Takahashi¹, Haruhisa Inoue^2,3,4 (1.Department of Neurology, Kyoto University Graduate School of Medicine, Japan, 2.Center for iPS Cell Research and Application (CiRA), Kyoto University, Japan, 3.iPSC-based Drug Discovery and Development Team, RIKEN BioResource Research Center, Japan, 4.Medical-risk Avoidance based on iPS Cells Team, RIKEN Center for Advanced Intelligence Project (AIP), Japan, 5.Department of Neurology, National Hospital Organization Sagamihara National Hospital, Japan, 6.Department of Clinical Neuroscience and Therapeutics, Hiroshima University Graduate School of Biomedical and Health Sciences, Japan, 7.Clinical Research Center and Department of Neurology National Hospital Organization Utano Hospital, Japan, 8.Department of Neurology, Koshokai Aobaoka Hospital, Japan, 9.Department of Neurology, Seirei Hamamatsu General Hospital, Japan)

Akihiko Mitsutake^1,2, Rimi Hino¹, Yuto Sakai², Takashi Matsukawa¹, Jun Mitsui³, Hiroyuki Ishiura^1,4, Nobue K. Iwata², Shoji Tsuji^3,5, Tatsushi Toda¹ (1.Department of Neurology, The University of Tokyo Hospital, Japan, 2.Department of Neurology, International University of Health and Welfare Mita Hospital, Japan, 3.Department of Precision Medicine Neurology, Graduate School of Medicine, The University of Tokyo, Japan, 4.Department of Neurology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Japan, 5.Institute of Medical Genomics, International University of Health and Welfare, Japan)

Ikuko Iwata¹, Niino Masaaki², Monami Tarisawa¹, Hisashi Uwatoko¹, Shinichi Shirai¹, Masaaki Matsushima¹, Hiroaki Yaguchi¹, Ganpei Nakahara³, Satoko Miyatake^4,5, Naomichi Matsumoto⁴, Ichiro Yabe¹ (1.Department of Neurology, Hokkaido University, Japan, 2.Department of Clinical Research, National Hospital Organization Hokkaido Medical Center, Japan, 3.Department of Neurology, Nakamura Memorial Hospital, Japan, 4.Department of Human Genetics, Yokohama City University Graduate School of Medicine, Japan, 5.Department of Clinical Genetics, Yokohama City University Hospital, Japan)