[Pe-050] English Poster Session 050「Motor neuron disease: Basic research 3」

Fri. May 31, 2024 5:15 PM - 6:35 PM Poster (Hall E, E Block, B2F, TIF)

Chair(s): Takuto Hideyama (Tokyo Medical University, Japan), Takehisa Hirayama (Department of Neurology, Toho University Faculty of Medicine, Japan)

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[Pe-050-1] Negative features of sporadic amyotrophic lateral sclerosis using ADAR2-conditional knockout mice

Takuto Hideyama, Sayaka Teramoto, Jun Yamazaki, Haruhisa Kato, Shin Kwak, Hitoshi Aizawa, Hiroo Terashi (Tokyo Medical University Hospital, Japan)

[Pe-050-2] Disruption of nuclear lamina and nucleoporins in FUS-ALS model mice, hiPSCs, and post-mortem tissue

Kensuke Okada¹, Daisuke Ito², Satoru Morimoto², Chris Kato², Yuki Oguma², Reona Kobayashi^2,3, Munehisa Shinozaki², Jin Nakahara¹, Shinichi Takahashi^2,4, Yoshinori Nishimoto¹, Shinsuke Shibata^2,5, Hideyuki Okano^2,3 (1.Department of Neurology, Keio University School of Medicine, Japan, 2.Department of Physiology, Keio University School of Medicine, Japan, 3.Laboratory for Marmoset Neural Architecture, RIKEN Center for Brain Science, Japan, 4.Department of Neurology and Stroke, Saitama Medical University International Medical Center, Japan, 5.Division of Microscopic Anatomy, Graduate School of Medical and Dental Sciences, Niigata University, Japan)

[Pe-050-3] Discovery of genetic modifiers regulating RAN translation using C9orf72-linked ALS/FTD fly model

Yuzo Fujino^1,2, Toshiki Mizuno², Yoshitaka Nagai¹ (1.Department of Neurology, Kindai University Faculty of Medicine, Japan, 2.Department of Neurology, Kyoto Prefectural University of Medicine, Japan)

[Pe-050-4] Expression of MMP-9 in degenerating spinal motor neurons in a mice model of sporadic ALS

Jun Yamazaki, Takuto Hideyama, Sayaka Teramoto, Makiko Naito, Haruhisa Kato, Hitoshi Aizawa, Shin Kwak, Hiroo Terashi (Department of Neurology, Tokyo Medical University Hospital, Japan)

[Pe-050-5] Establishement of an Anxa11 mutant mouse model associated with amyotrophic lateral sclerosis

Qing Liu, Dongchao Shen, Ye Sun, Liying Cui (Department of Neurology, Peking Union Medical College Hospital, Peking, China)

[Pe-050-6] E. coli-derived amyloid protein curli shortens the lifespan of neurodegenerative model Drosophila

Fukiko Kitani-Morii^1,2, Anh Huynh Man³, Hideki Yoshida³, Friedland Robert⁴, Takashi Kasai¹ (1.Department of Neurology, Kyoto Prefectural University of Medicine, Japan, 2.Department of Molecular Pathobiology of Brain Diseases, Kyoto Prefectural University of Medicine, Japan, 3.Department of Applied Biology, Kyoto Institute of Technology, Japan, 4.Department of Neurology, University of Louisville School of Medicine, USA)