Yohei Misumi¹, Luigetti Marco², Quan Dianna³, Berk John L.⁴, Conceição Isabel⁵, Chao Chi-Chao⁶, Bender Shaun⁷, Aldinc Emre⁷, Vest John⁷, Adams David⁸ (1.Department of Neurology, Graduate School of Medical Sciences, Kumamoto University, Japan, 2.Fondazione Policlinico Universitario A. Gemelli IRCCS - Universita Cattolica del Sacro Cuore, Italy, 3.Department of Neurology, University of Colorado Anschutz, USA, 4.Boston Medical Center, USA, 5.Department of Neurology, CHULN, Hospital Santa Maria and Faculdade de Medicina, Universidade de Lisboa, Portugal, 6.Department of Neurology, National Taiwan University Hospital, Taiwan, 7.Alnylam Pharmaceuticals, USA, 8.Neurology Department, CHU Bicetre, APHP, Universite Paris-Saclay, France)

Yasuyoshi Kimura¹, Toru Koda², Hiroyuki Kurakami^2,3, Shigeru Sakamoto², Koji Iwasaki², Hideki Mochizuki¹ (1.Department of Neurology, Osaka University Graduate School of Medicine, Japan, 2.Osaka University Hospital, Japan, 3.Nara Medical University, Japan)

Go Fujino¹, Asuka Kitamura¹, Akiko Takahashi¹, Meiko Maeda¹, Akatsuki Kubota¹, Yukino Tokuyama², Ikue Wada², Kazuhiro Kobayashi³, Hirofumi Komaki⁴, Mariko Taniguchi-Ikeda⁵, Keiko Ishigaki⁶, Tatsushi Toda¹ (1.Department of Neurology, Graduate School of Medicine, The University of Tokyo, Japan, 2.Clinical Research Promotion Center, The University of Tokyo Hospital, Japan, 3.Division of Molecular Brain Science, Kobe University Graduate School of Medicine, Japan, 4.Department of Child Neurology, National Center Hospital, National Center of Neurology and Psychiatry, Japan, 5.Department of Clinical Genetics, Fujita Health University Hospital, Japan, 6.Department of Pediatrics, Tokyo Women's Medical University School of Medicine, Japan)

Haruhiko Banno¹, Taro Okunomiya¹, Takayuki Kondo¹, Yoko Amino¹, Akiyoshi Nakakura¹, Harue Tada¹, Satoshi Morita¹, Akihiro Shindo², Takakuni Maki¹, Manabu Ikeda³, Yuishin Izumi⁴, Kazutomi Kanemaru⁵, Kenji Ishii⁵, Kazue Shigenobu⁶, Yoshihide Sunada⁷, Shinobu Kawakatsu⁸, Noriyuki Matsukawa⁹, Ryosuke Takahashi¹, Hidekazu Tomimoto², Haruhisa Inoue¹, REBRAnD investigators REBRAnD investigators^1,2,3,4,5 (1.CiRA/iACT/Department of Neurology, Kyoto University, Japan, 2.Department of Neurology, Mie University, Japan, 3.Department of Psychiatry, Osaka University, Japan, 4.Department of Neurology, Tokushima University, Japan, 5.Department of Stroke/Neurology, Research Team for Neuroimaging, Tokyo Metropolitan Institute for Geriatrics and Gerontology, Japan, 6.Department of Neuropsychiatry, Asakayama Hospital, Japan, 7.Department of Neurology, Kawasaki Medical School, Japan, 8.Department of Neuropsychiatry, Aizu Medical Center, Fukushima Medical University, Japan, 9.Department of Neurology, Nagoya City University, Japan)

Akira Tamaoka¹, Mitsuhiro Isozaki², Yasumasa Yoshiyama³, Katsunori Yokoi⁴, Chigusa Watanebe⁵, Hironori Tatsuda⁶, Ryoto Ozaki⁶, Takaaki Ishida⁶, Janice Smith⁷, Takashi Asada⁸ (1.Department of Neurology, Faculty of Medicine, University of Tsukuba, Japan, 2.Memory Clinical Toride, Japan, 3.Inage Neurology and Memory Clinic, Japan, 4.Department of Neurology, National Center for Geriatrics and Gerontology, Japan, 5.Department of Neurology, National Hospital Organization Hiroshimanishi Medical Center, Japan, 6.Chugai Pharmaceutical Co., Ltd, Japan, 7.Roche Products Ltd, Switzerland, 8.Tokyo Medical and Dental University, Japan)