Kazuo Fujihara^1,2, Yoshito Nagano³, Yoshikazu Naito⁴, Hideaki Hida⁴, Saori Yamauchi⁴, Muneyoshi Kudo⁴, Satoshi Yuki⁴, Shinya Hirota⁴, Kyoko Kato⁴ (1.Department of Multiple Sclerosis Therapeutics, Fukushima Medical University, Japan, 2.Southern TOHOKU Research Institute for Neuroscience, Japan, 3.Shion Daini Clinic, Japan, 4.Mitsubishi Tanabe Pharma Corporation, Japan)

Shinya Hirota¹, Kyoko Kato¹, Yoshikazu Naito¹, Yoshito Nagano², Hideaki Hida¹, Saori Yamauchi¹, Muneyoshi Kudo¹, Satoshi Yuki¹, Kazuo Fujihara^3,4 (1.Mitsubishi Tanabe Pharma Corporation, Japan, 2.Shion Daini Clinic, Japan, 3.Department of Multiple Sclerosis Therapeutics, Fukushima Medical University, Japan, 4.Southern TOHOKU Research Institute for Neuroscience, Japan)

Akihiro Ueda^1,2, Sayuri Shima², Toshiki Maeda², Masami Mizuno², Reiko Odake², Akira Sato¹, Yuji Tsujimura², Konoka Kanda², Syoko Nakano², Kunihisa Kato², Atsuhiro Higashi², Koichi Kikuchi², Ryunosuke Nagao², Seiko Hirota², Tomomasa Ishikawa¹, Yasuaki Mizutani², Mizuki Ito^2,3, Shinji Ito¹, Tatsuro Mutoh^2,4, Hirohisa Watanabe² (1.Fujita Health University Okazaki Medical Center, Japan, 2.Fujita Health University School of Medicine Department of Neurology, Japan, 3.Fujita Health University Bantane Hospital, Japan, 4.Fujita Health University Central Japan internasional Airport Clinic, Japan)

Yurino Horiuchi¹, Atsuko Katsumoto¹, Tomoko Okamoto¹, Youwei Lin^1,2, Wakiro Sato², Takashi Yamamura², Yuji Takahashi¹ (1.Department of Neurology, National Center Hospital, National Center of Neurology and Psychiatry, Japan, 2.Department of Immunology, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Japan)

Yasuhiro Hamada^1,2, Masashi Kino^2,3, Tadayuki Takata^1,2, Keita Takaba², Yuta Chiba⁴, Jun Kurimoto⁵, Shingo Aoe⁶, Yohei Kokudo⁴, Masaki Kamada^2,3, Wakako Nonaka^2,7, Makoto Kita², Kisaki Tachi², Tetsuo Touge², Kazushi Deguchi², Tsutomu Masaki² (1.Department of Supportive and Promotive Medicine of the Municipal Hospital, Faculty of Medicine, Kagawa University, Japan, 2.Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Japan, 3.Department of Neurological Intractable Disease Research, Faculty of Medicine, Kagawa University, Japan, 4.National Hospital Organization Takamatsu Medical Center, Japan, 5.Sanuki Municipal Hospital, Japan, 6.Sakaide Saint Martin's Hospital, Japan, 7.Department of General Medicine, Faculty of Medicine, Kagawa University, Japan)

Chikashi Yano, Eiji Matsuura, Tomonori Nakamura, Masahiro Ando, Yu Hiramatsu, Satoshi Nozuma, Yujiro Higuchi, Yusuke Sakiyama, Akihiro Hashiguchi, Kumiko Michizono, Keiko Higashi, Hiroshi Takashima (Department of Neurology, Kagoshima University Hospital, Japan)